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Modafinil is an oral drug that is used for improving wakefulness in patients with excessive sleepiness. It is similar to armodafinil (Nuvigil). Like amphetamines, modafinil promotes wakefulness by stimulatIng the brain. The exact mechanism of action of modafinil is unknown. It may work by increasing the amount of dopamine (a chemical neurotransmitter that nerves use to communicate with each other) in the brain by reducing the reuptake of dopamine into nerves. Modafinil was approved by the FDA in December 1998.

Side Effects Of Modafinil


The most common side effects of modafinil are as follows: headache, back pain, nausea, nervousness, stuffy nose, diarrhea, feeling anxious, trouble sleeping, dizziness, and upset stomach.


Other serious side effects include: a serious rash or allergic reaction including Stevens-Johnson Syndrome; rapid swelling beneath the skin; new mental health problems such as depression, anxiety, aggression, hallucinations, and thoughts of suicide; and symptoms of a heart problem including chest pain, abnormal heartbeat, and trouble breathing. In rare cases, modafinil can create a multi-organ hypersensitivity reaction, which can be life-threatening. Stop taking modafinil and seek medical attention immediately if you experience any of these serious side effects.